Detalhe da pesquisa
1.
Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes.
N Engl J Med
; 389(24): 2221-2232, 2023 Dec 14.
Artigo
Inglês
| MEDLINE | ID: mdl-37952131
2.
Esomeprazole FDA Approval in Children With GERD: Exposure-Matching and Exposure-Response.
J Pediatr Gastroenterol Nutr
; 65(3): 272-277, 2017 09.
Artigo
Inglês
| MEDLINE | ID: mdl-27875488
3.
Pharmacometrics-based dose selection of levofloxacin as a treatment for postexposure inhalational anthrax in children.
Antimicrob Agents Chemother
; 54(1): 375-9, 2010 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-19858256
4.
Concentration-QT relationships play a key role in the evaluation of proarrhythmic risk during regulatory review.
J Clin Pharmacol
; 48(1): 13-8, 2008 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-18094216
5.
Optimising piperacillin/tazobactam dosing in paediatrics.
Int J Antimicrob Agents
; 30(4): 320-4, 2007 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-17631983
6.
Non-linear mixed-effects pharmacokinetic/pharmacodynamic modelling in NLME using differential equations.
Comput Methods Programs Biomed
; 76(1): 31-40, 2004 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-15313540
7.
Ethnic differences in insulin sensitivity, ß-cell function, and hepatic extraction between Japanese and Caucasians: a minimal model analysis.
J Clin Endocrinol Metab
; 99(11): 4273-80, 2014 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-25119313
8.
Dosing rationale for liraglutide in type 2 diabetes mellitus: a pharmacometric assessment.
J Clin Pharmacol
; 52(12): 1815-23, 2012 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-22174428
9.
Population pharmacokinetic and concentration--QTc models for moxifloxacin: pooled analysis of 20 thorough QT studies.
J Clin Pharmacol
; 51(8): 1152-62, 2011 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-21228407
10.
Creation of a knowledge management system for QT analyses.
J Clin Pharmacol
; 51(7): 1035-42, 2011 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-20978278
11.
Population pharmacokinetic/pharmacodynamic (PK/PD) modelling of the hypothalamic-pituitary-gonadal axis following treatment with GnRH analogues.
Br J Clin Pharmacol
; 63(6): 648-64, 2007 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-17096678
12.
Semi-mechanistic pharmacodynamic modeling for degarelix, a novel gonadotropin releasing hormone (GnRH) blocker.
J Pharmacokinet Pharmacodyn
; 33(5): 609-34, 2006 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-16967346
13.
Non-linear mixed-effects models with stochastic differential equations: implementation of an estimation algorithm.
J Pharmacokinet Pharmacodyn
; 32(1): 85-107, 2005 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-16175312
14.
Stochastic differential equations in NONMEM: implementation, application, and comparison with ordinary differential equations.
Pharm Res
; 22(8): 1247-58, 2005 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-16078134
15.
Pharmacometrics as a discipline is entering the "industrialization" phase: standards, automation, knowledge sharing, and training are critical for future success.
J Clin Pharmacol
; 50(9 Suppl): 9S-19S, 2010 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-20881213
16.
Pharmacokinetic/pharmacodynamic modelling of GnRH antagonist degarelix: a comparison of the non-linear mixed-effects programs NONMEM and NLME.
J Pharmacokinet Pharmacodyn
; 31(6): 441-61, 2004 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-16222784
17.
Grey-box modelling of pharmacokinetic/pharmacodynamic systems.
J Pharmacokinet Pharmacodyn
; 31(5): 401-17, 2004 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-15669774
18.
Population pharmacokinetic modeling of a subcutaneous depot for GnRH antagonist degarelix.
Pharm Res
; 21(4): 574-84, 2004 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-15139513